Accuracy of distortion-product otoacoustic emissions-based ototoxicity monitoring using various primary frequency step-sizes

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Accuracy of distortion-product otoacoustic emissions-based ototoxicity monitoring using various primary frequency step-sizes.

OBJECTIVE A cisplatin ototoxicity monitoring protocol was recently proposed using distortion-product otoacoustic emissions (DPOAEs) measured in 1/48th octave steps over the highest obtainable quarter octave ( Dille et al, 2010 ). This protocol can take up to 40 minutes to complete in both ears among seriously ill patients in a potentially noisy test environment. The goal of the current study wa...

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Distortion-product otoacoustic emission test performance for ototoxicity monitoring.

INTRODUCTION A nonbehavioral method for monitoring ototoxicity in patients treated with cisplatin is needed because patients enduring chemotherapy may not be well or cooperative enough to undergo repeated hearing tests. Distortion-product otoacoustic emissions (DPOAEs) provide a nonbehavioral measure of auditory function that is sensitive to cisplatin exposure. However, interpreting DPOAE findi...

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High-frequency hearing influences lower-frequency distortion-product otoacoustic emissions.

OBJECTIVES The primary goal of this study was to test the ability of 2f1-f2 distortion-product otoacoustic emissions (DPOAEs) to detect reduced cochlear function in the presence of normal behavioral sensitivity. DESIGN A prospective study was performed in normal-hearing young adults using simple and complex regression analyses to clarify the relationship between ultra-high frequency (UHF) hea...

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Distortion product otoacoustic emissions in tinnitus patients.

Tinnitus is a symptom that affects a great number of patients. Its diagnosis, treatment, and follow-up are difficult, owing to its subjectivity. The authors propose the use of distortion product otoacoustic emissions (DPOAEs) in tinnitus evaluation. They studied three groups: controls, having no complaint of tinnitus and normal hearing; group 1, presenting tinnitus and normal audiometry; and gr...

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Ototoxicity risk assessment combining distortion product otoacoustic emissions with a cisplatin dose model.

An objective method for identifying ototoxic hearing loss among patients receiving cisplatin is necessary since the ability of patients to take a behavioral test may change over the course of treatment. Data from 56 monitoring visits by 19 Veterans taking cisplatin were used to identify combinations of distortion-product otoacoustic emission (DPOAE) metrics and ototoxicity risk factors that bes...

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ژورنال

عنوان ژورنال: International Journal of Audiology

سال: 2012

ISSN: 1499-2027,1708-8186

DOI: 10.3109/14992027.2012.688143